Methylmercury

Methylmercury Chloride Coaxed Oxidative Stress in Rats

The present experiment was designed to access the effects of Methylmercury chloride ( MeHgCl) on antioxidant status, protein concentration, lipid peroxidation and hydroperoxidation in brain parts, spinal cord, lung, heart and pancreas of rats. Twenty male Wistar rats (3 months old) were divided in saline controls (C) and MeHgCl-treated group (MMC). Treated rats were intoxicated with MMC ...

[Metabolismes of methylmercury sulfate and methylmercury iodide in animals].

Cats fed (CH3Hg)2SO4 developed the same findings as spontaneously affected cats fed the poisonous seafood from Minamata Bay. The organomercury compound in raw organs such as the liver, the kidney, and the bone marrow of the above animals did not transfer to chloroform , but it transferred easily to BAL. The methylmercury compound in organs of cats fed (CH3Hg)2SO4 and rats fed CH3HgI accumulated...

Reference Dose for Methylmercury

Notice This document is a preliminary draft. It has not been formally released by EPA and should not at this stage be construed to represent Agency policy. It is being circulated for comment on its technical accuracy and policy implications.

Reference Dose for Methylmercury

Methylmercury neurotoxicity & antioxidant defenses.

Neurotoxicity induced by methylmercury (MeHg) increases the formation of reactive radicals and accelerates free radical reactions. This review summarizes recent findings in the MeHg-induced formation of free radicals and the role of oxidative stress in its neurotoxicity. Oxidative stress on CNS can produce damage by several interacting mechanisms, including mitochondrial damage with increase in...